Childhood Cancer

Meet 2023 Ambassador Jonah: A Rare Gift

by St. Baldrick's Foundation
January 23, 2023

The best gifts are the ones that make us smile and fill our hearts with joy. When we are lucky enough to receive such a gift, we find ourselves filled with gratitude. 

Jonah is this kind of gift — to his family, to his friends and to those he meets every day. Despite having faced childhood cancer, he is, in his mum’s words, “the most kind, inclusive, loving, welcoming, forgiving heart while also being the hardest working person you’ll ever meet.” 

It doesn’t seem to add up—Jonah has every reason to be discouraged, defeated and even angry because of the impact childhood cancer has had on his life. But when you meet this survivor, you can see that childhood cancer doesn’t define him and you can’t deny that he is a gift. This is Jonah’s story. 

Jonah sitting on lifeguard stand at the beach.

Jonah at the beach in 2021.

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Head-Shaving

5 Reasons to Start a Head-Shaving Event [VIDEO]

by St. Baldrick's Foundation
January 20, 2023

Do you like bringing people together? Do you want to make a difference for kids with cancer? We do, too! Join St. Baldrick’s and throw the ultimate party for good — a head-shaving event. Read on for five reasons to organize your own amazing event this year.

Woman shaving head for cancer at St. Baldrick's event

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Childhood Cancer

Meet 2023 Ambassador Hanna: A Lesson in Rising Above the Storm

by St. Baldrick's Foundation
January 17, 2023

Life can be unfair. Curveballs, challenges, and heartaches do not discriminate. Even for the nicest people you know. 

But there’s a popular quote that promises, “rise above the storm and you will find the sunshine.” 

Meet Hanna. She has embodied this quote for 29 years, rising above the unfair hand she was dealt to feel the sunshine on her face. 

Meet Hanna (no extra “h” at the end please). 

Photo of Hanna

Hanna

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Events and Fundraisers

7 Things That Will Happen at Your St. Baldrick’s Event

by St. Baldrick's Foundation
January 13, 2023

So many awesome things happen at St. Baldrick’s events that it was tough to whittle the list down to seven. But here they are! Read on for the seven stupendous things that will happen at your St. Baldrick’s event.

Man getting his head shaved

1. You will make an impact

St. Baldrick’s volunteers are changing the world for kids with cancer. With $325 million going to research in 31 countries, we’re making a big impact on childhood cancer research — and it’s all thanks to you. Keep up the great work!

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Research

Celebrating Four New St. Baldrick’s Foundation Research Grants

by St. Baldrick's Foundation
January 12, 2023

Announcing $400,000 in new research grants next to science laboratory equipment

January is usually a time to relax after holiday celebrations – but we aren’t done celebrating yet. Because of the support of St. Baldrick’s Hero Funds and donors like you, we can celebrate four new research grants this month.

These grants were made in response to a specific Request For Applications in disease areas in which St. Baldrick’s typically sees a low number of applications.

Dr. Mitchell Cairo will work to develop immunotherapeutic agents to enhance the functions of Natural Killer cells to kill Burkitt lymphoma. Natural Killer cells are type of immune cell that can kill cancer cells. If successful this would offer a potentially more effective and less toxic treatment option, ultimately leading to improved survival. This grant is supported by the Jack’s Pack – We Still Have His Back Hero Fund.

Dr. Saba Ghassemi is working to develop CAR T cells faster and with increased strength to fight pediatric glioblastoma (GBM). She will combine these CAR T cells with a metabolic strategy to overcome the metabolic nature of tumor environment. This will lead to superior immunotherapy treatments against pediatric GBM. This grant is supported by the Be Brooks Brave Fund Hero Fund.

Ewing sarcoma, an aggressive bone cancer that occurs in children and young adults, is caused by an abnormal protein (EWS-FLI1) that stops cells from maturing into normal tissues. Dr. Joseph Ludwig is using powerful gene editing tools to systematically turn the EWS-FLI1 protein up or down and then measure whether such changes allow cancer cells to behave more normally. The information gained from this research is expected to lead to new anti-cancer treatments for adolescents and young adults battling Ewing sarcoma. This grant is supported by the Shohet Family Fund for Ewing Sarcoma Research Hero Fund.

Dr. Kimberly Stegmaier and colleagues have used a technology called CRISPR to identify new therapeutic targets for Ewing sarcoma. They prioritized a class of targets which are expressed in immature but not mature tissues. These proteins are often abnormally re-expressed in cancers such as Ewing sarcoma. Thus, drugs targeting these proteins would be expected to have minimal toxicity. Dr. Stegmaier will validate these therapeutic targets in Ewing sarcoma. This project has exciting translational potential for patients with Ewing sarcoma. This grant is supported by the The Ben Brandenburg Fund for Ewing Sarcoma Research Hero Fund.

As we look ahead into 2023 and beyond, this research gives kids with cancer hope. Keep a look out for our next grants announcement later this Spring. To learn more about the Hero Fund program check out this blog.

Donate now and help support research into better treatments for kids with cancer.

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Childhood Cancer

Meet 2023 Ambassador Jaron: A YouTube Star with a Heart for Others

by St. Baldrick's Foundation
January 9, 2023

“Hi everybody! Welcome back to Jaron’s Toys.”

Jaron holding his dog, Chloe.

Jaron with his dog, Chloe.

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Childhood Cancer

Meet 2023 Ambassador Mia: An Extraordinary Kindergartener with a Mega-Watt Smile

by St. Baldrick's Foundation
January 6, 2023

Mia is no ordinary girl; in fact, she is EXTRA-ordinary! This spunky, fun-loving, energetic kindergartener is full of imagination.

Mia in hospital room during chemotherapy treatment.

Mia in hospital during chemotherapy treatment.

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Childhood Cancer

Meet the 2023 St. Baldrick’s Ambassadors!

by St. Baldrick's Foundation
January 4, 2023

St. Baldrick’s Ambassadors represent the wide diversity of kids diagnosed with childhood cancers. Their stories highlight the importance of supporting the best childhood cancer research so all kids diagnosed can live long, healthy, productive and happy lives.

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Childhood Cancer

What a Difference a Year Makes

by St. Baldrick's Foundation
December 8, 2022

A year ago, Sage was as excited as any 4-year-old at Christmastime. His family had no idea how much their lives would change just a month later.

Sage opening presents on Christmas Day 2021

Sage opening presents on Christmas Day 2021

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Research

2022 Infrastructure Grants to Support Clinical Trials

by St. Baldrick's Foundation
November 21, 2022

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